FUNDAMENTALS OF BIOLOGICAL PHARMACY
VS
KUMBH BATH & KALPWAS
By – *Prof. Y.B.Tripathi, **Dr. Vachaspati Tripathi
Kumbh Bath and Kalpwas : are practiced in the sanatany system of Hindu mythology since time immemorial. It was treated as very important and necessary for the individual’s well being, and was consider to be as precious as taking NECTOR to save life. These communal baths are usually held during the winter season at Prayag, Haridwar, Nasik, Ujjain and other places, after every six year, in the name of Kumbha, Ardh Kumbha and Maha Kumbha where lakhs of people take bath together.
Scientific facts are mentioned below based on the chapter of fundamentals of Biological Pharmacy written by Prof. Bernard Witlin, DSc, Prof. of Microbiology, Philadelphia collage of Pharmacy and science, Philadelphia, Pa19104. Mentioned in text book of Remington’s Pharmaceuticals science.
The correlation and expalation of Kumbha Bath and Kalpwas with scientific fact is mentioned below under heading entitled Kumbh bath and kalpwas.
Scientific Fact: Upon first exposure to a germ or other antigen (foreign bodies), several days may be required before an individual achieves peak production of antibodies. The antibodies are the defense proteins which are formed in cells of lymphoid series, when subjected to suitable antigenic stimulation.
Kumbh bath and kalpwas: provides the first exposure or stimulation of human being to several new germs or other antigens of known or unknown origins and appropriate antibodies are produced.
Scientific Fact: On subsequent exposure to the microorganisms however the body appears to remember the first trial and is ready to produce the appropriate antibody. This secondary response is fast and massive, often peaking within a few hours.
Kumbh bath and kalpwas : upon subsequent exposure to infections of known or unknown germ/microorganism/antigen anywhere in future, the body produces antibodies quickly and in a massive amount, with in a few hours - making the body immune to those infection/microorganism/antigen.
Scientific Fact: Each antibody is good for only one antigen and each antigen stimulates the production of only one antibody. The body may remember exposure to one virus. yet be unprepared for the virus’ first cousin.
Kumbh bath and kalpwas: the periodic nature of these baths is significant. The body develops the antibody against all germ/microorganism/antigen during the kumbha bath and kalpwas, and gets the immunity, but during the 6 years interval many new germs/microorganisms/antigens develop due to mutation, and bring genotypic change, for which normal human body is not immuned. For regular immunization kumbha bath provides periodic bath and kalpwas to –keep a person healthy against infectious disease ( Dangu, Chikangunia, T.B., and Aids are similar new diseases caused by new microbes.)
Scientific Fact: Immunity is described as a state of non susceptibility to infection. The degree and speed with which the invader (Bacteria-viruses and fungi) may do harm depend completely upon the resistance or lack of resistance of the host as a result of the development of an adequate level of immunity due to antibodies, the host developed resistance to the invasive power of infecting microorganisms or is capable of protecting itself against the deleterious action of their toxic products.
Kumbh Bath and Kalpwas : the antibodies prepared for different invaders after the bath makes man immune and thus protect itself against the infection and its bad effect.
Scientific Fact: infections when the natural barriers of the body fail to prevent entrance of microorganisms, infection may result if such organisms are pathogenic.
Kumbh bath and Kalpwas : In the time interval between Kumbh bath, the man/human body is infected naturally and if the body is not immuned the body or host is incapable of withstanding the attack, hence the host/man develops the disease, progress and may even terminate fatally.
Scientific Fact : In routine immunological studies, protective antibodies to a variety of infections are found in individual.
Kumbh Bath and Kalpwas: The chances of infection becomes more if more infection bearing men, take bath together at scheduled "Kumbh"-Ghada place, these infection generate protective antibodies to a variety of infections.
Scientific Fact: The degree of immunity possessed is the determining Scientific Factor in successful resistance against future exposures. Some times the immunity may be ineffective in the event of exposure to an overwhelming dose of infective organism. Individuals in good health are endowed with a high level immunity; in winter anabolic rate of body increases this offering good general level of health contributes to immunity.
Kumbh Bath and Kalpwas: It occurs during winter season when the temperature of water is about 7-12°C. Which attenuates the breeding of microorganism thus preventing an over whelming dose of infectants from spreading into water, During the Kalpwas people eat nutritious diet in several “AKHADA” thus individual attains good health and develops maximum degree of immunity which is sufficient for successful resistance.
Scientific Fact:.
Scientific Fact: Antibodies occur in response to infection or antigen in the body. Sensitization or invasion may develop as a result of ingestion, dermal contact or even of inhalation of provoking agents.
Kumbh Bath and Kalpwas: The bath at kumbh or “Ghada” specific spot provides for ingestion, dermal contact or even of inhalation of provoking agents, which stimulates production of antibodies.
Scientific Fact: The antibodies produced are generally specific for the antigen which caused their production and are usually demonstrable in the blood serum and other body fluids. The antibodies are particularly associated with the globulin fractions of the protein content of the blood serum.
Kumbh Bath and Kalpwas: The above Scientific Fact can be tested and the importance of Kumbh Bath and Kalpwas can be established.
Scientific Fact: The generic term applicable to a wide variety of substances which are antagonistic to or capable of neutralizing the antigens responsible for their production is antibodies. These include antitoxin, agglutinins, lysine and precipitins. Other antibodies may be bacterio static, bactericidal or virucidal. Many common diagnostic tests are based on antigen-antibody reactions. Clinically, antibodies are distinguished as being antibacterial (antiviral), and as being antitoxin. Specific antibodies are reactive only against the substance which stimulated their production.
Kumbh Bath and Kalpwas: Thus the antibodies form due to unknown-known stimulate of antigen and they are specific to unknown – known stimuli hence the assumptions becomes true that Kumbh Bath and Kalpwas generate immunity against many new diseases including Chikan Guinea, Dangu, Hey fewer & AIDS, T.B. etc.
Scientific Fact: If protection is acquired accidentally or artificially, it is called acquired immunity, here the antibodies produced at some time after birth, the two kind of acquired immunity are active acquired immunity and passive acquire immunity.
Natural
Active
Acquired Immunity Artificial
Natural
Passive
Artificial
The biological pharmacy is based on the principle of acquired immunity. General good health implies healthy body tissues, skin and mucous membranes, all important bacterial barriers of good quality, leukocytes in plentiful supply and properly active and so forth.
Infectious diseases vary considerably among species, races and even among individual on to age and sex. Some ninety diseases-T.B., Anthrax, Psillacosis, rabies occur in man and animal alike, wile disease such as syphilis, measles, leprosy, gonorrhea, mumps, typhoid fever, dysentery, whooping cough, etc. have not yet been shown in animals. Races also affect susceptibility to tuberculosis. The resistance of an individual in a given community may also vary greatly, although it must be recognized, it is attributed to acquired immunity, which had developed due to previous contact. Nutritional well being and fatigue also affect the resistance.
Kumbh Bath and Kalpwas: the crore people taking bath together provide infection of microbes which generally affect the subject. Also the community difference in immunity supports the thought of Hindu Sant, Rishis and Mythology. Thus people of different communities which take bath at Kumbh develop more immunity.
Scientific Fact: Acquired immunity develops in response to specific stimulus i.e. the introduction of foreign substances is called Active Acquired Immunity; it is acquired by having 1.disease, 2. by single or repeated exposure to sub-infections dose of the disease organism or 3. by being treated usually by injection with the modified disease organisms or their derivatives (Vaccination). When resistance is developed following active contact with disease organisms under normal conditions the resulting immunity is termed as Natural Acquired Immunity, Immunity produced by vaccination following the injection of toxins, attenuated toxins. (toxoids), allergenic products, or live attenuated or killed microorganism or their products is designated as being artificially acquired immunity. The end products of both instances are presumed to be the same. Natural acquired immunity is developed slowly, depending upon many factors, including the antigenicity of the organisms, the durations, or at times, repetitiveness of the organism invasion or diseases.
Kumbh Bath and Kalpwas: The people may bear many infections; they take bath together and thus infect each other, this favors the natural active acquired immunity principle. More over Kalpwas and 5 specific bath their specific duration, times and repetitiveness of the invasion result in increased immunity.
Scientific Fact: The duration of active immunity is quite variable, brief to many years and in some cases last for life.
Kumbh Bath and Kalpwas: Thus periodic bath after 6 years attribute immunity to the subject human life long against many unknown-known microbes.
Scientific Fact: hypersensitivity The Biological products include vaccines, antigens and toxoids. The use of biological products results in serum sickness, anaphylaxis, allergy, drug and food idiosyncrasies etc. it is called hypersensitivity. Serum sickness is characterized by the formation of rash, urticaria, skin eruption, edema or swelling joint pains, and some times by a slight fever. It is similar to shock.
Kumbh Bath & Kalpwas: do not cause hypersensitivity as is a natural process.
Kumbh Bath and Kalpwas: Thus Kumbh bath and kalpwas, its procedure, time, duration, season, atmosphere and lifestyle attribute natural active acquired immunity with almost no hypersensitivity and low cost basis. It also provides immunity against so many known and unknown microbes or pathogen for which there is no procedure in artificial acquired immunity. Nectar is defined as a drop of which, when taken can save life of man from death. Kumbh bath and kalpwas save the life of man from death usually occurs due to infectious diseases due to principle of natural active acquired immunity of biological pharmacy. People may remember that days when Kalajar, Plague etc. took the life of all community or village town, the similar disease may happened earlier caused great loss to humanity, for which the saint and rishis understood the logical cause and established the importance/necessity of Kumbha bath and kalpwas as the Amrita pan. Hence Kumbh bath and kalpwas is a way to resist death due to infection and may undoubtedly be treated as “Amrit Pan”.
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*Prof. Y,B.Tripathi
Department of Biochemistry, IMS,BHU – Varanasi
** Dr. Vachapati Tripathi
Pharmaceutical Scientist, B.Pharma. (Hons.), M. Pharma, IT BHU
S.R.F., U.G.C. (Dept. of Medicinal Chemistry, Faculty of Ayurveda)
S.R.F., U.G.C. ` (Dept. of Pharmacology, Institute of Medical Sciences)
Proprietor – Surya Pharmaceuticals
Managing Director – Surya Neutraceuticals Pvt. Ltd.
General Secretary – Prof. S.N. Tripathi Memorial Foundation
Member Expert Committee on Bhasma, DST, GOI
President Sanatan Sanskrit Kendra
Former Member National Committee for Natural Products
Planning Commission, GOI
S.R.F., U.G.C. (Dept. of Medicinal Chemistry, Faculty of Ayurveda)
S.R.F., U.G.C. ` (Dept. of Pharmacology, Institute of Medical Sciences)
Proprietor – Surya Pharmaceuticals
Managing Director – Surya Neutraceuticals Pvt. Ltd.
General Secretary – Prof. S.N. Tripathi Memorial Foundation
Member Expert Committee on Bhasma, DST, GOI
President Sanatan Sanskrit Kendra
Former Member National Committee for Natural Products
Planning Commission, GOI
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